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Influence of Additional Reaction Conditions

Overview

In addition to temperature and pressure, various further conditions can influence the position of a chemical equilibrium. In this chapter, the focus is on how such “additional” factors change concentrations, activities, or effective reaction pathways, and how this leads to a shift of the equilibrium position according to the law of mass action and Le Châtelier’s principle.

We will consider:

Temperature- and pressure-effects on equilibrium are treated separately in their own chapter and are therefore not discussed in detail here.

Changes in Concentration of Reactants and Products

For a general reaction

$$
a\,\mathrm{A} + b\,\mathrm{B} \rightleftharpoons c\,\mathrm{C} + d\,\mathrm{D},
$$

the equilibrium constant (for activities or, in dilute solutions, concentrations) is

$$
K = \frac{[\mathrm{C}]^c[\mathrm{D}]^d}{[\mathrm{A}]^a[\mathrm{B}]^b}.
$$

At a given temperature, $K$ is constant. However, the actual ratio of concentrations may temporarily deviate from $K$ when conditions change. The reaction quotient

$$
Q = \frac{[\mathrm{C}]^c[\mathrm{D}]^d}{[\mathrm{A}]^a[\mathrm{B}]^b}
$$

describes the current state. If $Q \neq K$, the system will evolve until $Q = K$ again.

Addition of a Reactant

Adding more of a reactant (e.g. increasing $[\mathrm{A}]$) changes $Q$:

Qualitatively: adding a reactant shifts the equilibrium towards products.

Example: For

$$
\mathrm{N_2(g)} + 3\,\mathrm{H_2(g)} \rightleftharpoons 2\,\mathrm{NH_3(g)},
$$

at constant $T$ and $P$, adding $\mathrm{N_2}$ or $\mathrm{H_2}$ increases the equilibrium amount of $\mathrm{NH_3}$.

Removal of a Reactant

Removing a reactant (e.g. decreasing $[\mathrm{A}]$) has the opposite effect:

Qualitatively: removing a reactant shifts the equilibrium towards reactants.

Addition or Removal of a Product

Analogously:

Many industrial processes exploit this by continuously removing a product (e.g. by distillation, absorption, crystallization, or gas stripping) to “pull” the equilibrium toward product formation.

Influence of Inert Gases

Inert gases (e.g. $\mathrm{Ar}$, $\mathrm{N_2}$ in some contexts) do not participate chemically in the reaction. Nevertheless, they can change partial pressures and thereby affect equilibria involving gases. The effect depends critically on whether volume or pressure is held constant.

Addition of an Inert Gas at Constant Volume

If the volume $V$ is held constant and an inert gas is added, the total pressure increases, but the partial pressures (and thus the concentrations) of the reacting gases remain unchanged:

Therefore:

So: adding an inert gas at constant volume does not affect the equilibrium position.

Addition of an Inert Gas at Constant Pressure

If the total pressure is held constant and an inert gas is added, the system must expand (volume increases) to keep the total pressure unchanged.

The direction of the subsequent equilibrium shift depends on the stoichiometric change in the number of gaseous moles, $\Delta n_{\text{gas}}$:

Thus, at constant pressure, adding inert gas can indirectly influence the equilibrium of gas-phase reactions through changes in concentrations.

Solvent and Ionic Strength Effects

In solution, equilibrium constants are properly expressed in terms of activities $a_i$, not simple concentrations. For dilute systems, activities are often approximated by concentrations, but this approximation can fail as ionic strength or solvent composition changes.

Change of Solvent or Solvent Composition

Changing the solvent (or mixing solvents) alters:

These factors modify the relative stabilization of reactants and products and therefore the equilibrium constant $K$ itself.

Qualitative rules:

Thus, simply dissolving the same reacting substances in a different solvent (e.g. water vs. ethanol) can result in a different equilibrium composition.

Ionic Strength and Activity Coefficients

For ionic equilibria (e.g. acid–base equilibria, solubility equilibria, complex formation), the ionic strength $I$ of the solution plays a central role. It influences the activity coefficients $\gamma_i$ of ions:

$$
a_i = \gamma_i \,[i].
$$

As ionic strength increases:

Because equilibrium expressions are written in terms of activities, changing the ionic strength shifts the apparent equilibrium position when expressed in concentrations. This is important in:

Influence of pH

For reactions involving species that can be protonated or deprotonated, the pH of the solution is a crucial additional condition. Many equilibria are coupled to acid–base equilibria.

General Principle

If a species in an equilibrium can be converted (by protonation or deprotonation) into a form that does not appear in the equilibrium expression, this removal or addition effectively shifts the equilibrium.

Example pattern:

pH Control as a Tool

By setting and maintaining a specific pH (using buffers, acids, or bases), chemists can:

For example, many metal hydroxides precipitate at higher pH due to

$$
\mathrm{M^{n+}} + n\,\mathrm{OH^-} \rightleftharpoons \mathrm{M(OH)_n(s)},
$$

so increasing $[\mathrm{OH^-}]$ (raising pH) pushes the equilibrium to the right, promoting precipitation.

Complex Formation and Precipitation as Driving Forces

Some reactions can be made to appear “irreversible” in practice when a product is removed from the equilibrium mixture through a secondary process—such as complexation, precipitation, or gas removal. These additional conditions change the effective equilibrium position of the original reaction.

Complexation

If a product of a reaction forms a stable complex with another species that is not part of the original equilibrium, the free (uncomplexed) concentration of that product decreases.

Consider:

$$
\mathrm{M^{2+}} + \mathrm{L} \rightleftharpoons \mathrm{ML^{2+}} \quad (K_1)
$$

If the complex $\mathrm{ML^{2+}}$ then binds further ligands:

$$
\mathrm{ML^{2+}} + 3\,\mathrm{L} \rightleftharpoons \mathrm{ML_4^{2+}} \quad (K_2),
$$

the equilibrium between $\mathrm{M^{2+}}$ and ligand $\mathrm{L}$ is effectively shifted towards complexed forms. For another equilibrium involving $\mathrm{M^{2+}}$, the free $\mathrm{M^{2+}}$ concentration becomes much lower than without complexation, which shifts that other equilibrium.

Practical implications:

Precipitation

For a solubility equilibrium

$$
\mathrm{AB(s)} \rightleftharpoons \mathrm{A^+ (aq)} + \mathrm{B^- (aq)},
$$

the solubility product is

$$
K_\text{sp} = [\mathrm{A^+}][\mathrm{B^-}].
$$

If any process reduces either $[\mathrm{A^+}]$ or $[\mathrm{B^-}]$ (e.g. by forming an insoluble salt or complex), the equilibrium shifts to produce more of that ion, often leading to more precipitation of the solid. Conversely, complex formation with one of the ions can increase solubility by lowering the free ion concentration and thereby allowing more solid to dissolve to maintain $K_\text{sp}$.

Thus, by introducing precipitating or complexing agents, one can control solubility equilibria and thereby indirectly force other coupled equilibria to shift.

Gas Removal or Supply

For equilibria involving gases dissolved in or in contact with a liquid, changing the partial pressure of the gas above the solution acts as an “additional condition.”

For example, for dissolution of a gas:

$$
\mathrm{CO_2(g)} \rightleftharpoons \mathrm{CO_2(aq)},
$$

and subsequent reaction:

$$
\mathrm{CO_2(aq)} + \mathrm{H_2O} \rightleftharpoons \mathrm{H_2CO_3(aq)},
$$

lowering the partial pressure of $\mathrm{CO_2}$ (e.g. by flushing with an inert gas, or lowering total pressure) reduces $[\mathrm{CO_2(aq)}]$, which shifts the carbonic acid–carbonate equilibria. Similarly, continuously removing a gaseous product from the reaction mixture (by sparging or vacuum) pulls the main equilibrium towards product formation.

Role of Catalysts: Kinetics vs. Equilibrium

Catalysts provide an important example of a condition that affects the rate at which equilibrium is reached but does not change the equilibrium position itself.

From the perspective of “shifting” equilibria:

This distinction—kinetic vs. thermodynamic control—is central when interpreting the influence of experimental conditions on observed compositions.

Summary

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